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What is point mutation? Give one example.

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What is point mutation? Give one example.

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Point mutation is a gene mutation that arises due to a change in a single base pair of DNA.

Example: Sickle-cell anaemia.

Substitution of a single nitrogen base at the sixth codon of the β- globin chain of haemoglobin molecule causes the change in the shape of the R.B.C. from biconcave disc to the elongated shaped, structure which results in sickle cell anaemia.

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