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Distinguish between Plasmid DNA and chromosomal DNA.

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Distinguish between Plasmid DNA and chromosomal DNA.

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Plasmid DNA is naked double-stranded DNA that forms a circle with no free ends. It is associated with few proteins. It is smaller than the host chromosome and can be easily separated.

Chromosomal DNA is a double-stranded linear DNA molecule associated with large proteins. This DNA exists in relaxed and supercoiled forms and provides a template for replication and transcription. It has free ends.

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