If the couples are enabled birth to the children and corrections are not possible, the couples could be assisted to have children through certain special techniques, commonly known as Assisted Reproductive Technologies (ART).

Some methods are given as:

1. In Vitro Fertilization (IVF): In this method, ova from the female and the sperm from the male are collected and induced to form a zygote under simulated conditions in the laboratory. This process is called In Vitro Fertilization (IVF).

Some method is given as follows:

Zygote Intrafallopian Transfer (ZIFT): The zygote or early embryo with up to 8 blastomeres is transferred into the fallopian tube.

Intra-Uterine Transfer (IUT): Embryo with more than 8 blastomeres is transferred into the uterus in females who cannot conceive embryos formed by the fusion of gametes in another female are transferred.

Test tube baby: In this method, ova from the donor (female) and sperm from the donor (male) are collected and are induced to form a zygote under simulated conditions in the laboratory. The zygote could then be transferred into the fallopian tube and embryos transferred into the uterus, to complete its further development. The child born from this method is called a test-tube baby.

2. Gamete Intra Fallopian Transfer (GIFT): It is the transfer of an ovum collected from a donor into the fallopian tube 8 another female who cannot produce one, but can provide a suitable environment for fertilization and further development of the embryo.

3. Intra Cytoplasmic Sperm Injection (ICSI): It is a procedure to form an embryo HI the laboratory by directly injecting the sperm into an ovum.

4. Artificial Insemination (AI): In this method, the semen collected either from the husband or a healthy donor is artificially introduced into the vegina or into the uterus (Intra Uterine Insemination, IUI). This technique is used in cases where the male is unable to inseminate sperms in the female reproductive tract or due to very low sperm counts in the ejaculation.

5. Host Mothering: In this process, the embryo is transferred from the biological mother to a surrogate mother. The embryo then develops till it is fully developed or partially developed. It is then transferred to the biological mother or into any other. This technique is useful for females in which embryo forms but is not able to develop.