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Assertion: Failure of secretion of hormone vasopressin causes diabetes mellitus in the patient.

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Assertion: Failure of secretion of hormone vasopressin causes diabetes mellitus in the patient.

Reason: Vasopressin increases the volume of urine by increasing the reabsorption of water from the urine.

(a) If both Assertion and Reason are correct and Reason is the correct explanation of Assertion.

(b) If both Assertion and Reason are correct, but Reason is not the correct explanation of Assertion.

(c) If Assertion is correct but Reason is incorrect.

(d) If both the Assertion and Reason are incorrect.

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(d) If both the Assertion and Reason are incorrect.

Explanation:

Vasopressin or anti-diuretic hormone (ADH) reduces the volume of urine by increasing the reabsorption of water from the urine in the distal convoluted tubules, collecting tubules and collecting ducts in the kidney. It does so by rendering the walls of these tubules leads to diabetes insipidus (increased urination). Although the volume of urine is increased. No glucose appears in the urine of such patients.

Diabetes mellitus is a disease which is caused due to the failure of insulin hormone secretion by the pancreatic islets. The osmotic effect of glucose in the urine considerably increases the volume of urine, due to which thirst is also enhanced. In extreme cases, the patient suffers from coma and may die.

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