Assertion: Persons suffering from haemophilia fail to produce blood clotting factor VIII.
Reason: Prothrombin producing platelets in such persons are found in very low concentration.
(a) If both Assertion and Reason are correct and Reason is the correct explanation of Assertion.
(b) If both Assertion and Reason are correct, but Reason is not the correct explanation of Assertion.
(c) If Assertion is correct but Reason is incorrect.
(d) If both the Assertion and Reason are incorrect.
(c) If Assertion is correct but Reason is incorrect.
Explanation:
Haemophilia bleeding disorder is a group of hereditary genetic disorders that impair the body’s ability to control blood clotting or coagulation. In its most common form, Hemophilia A, clotting factor VIII is absent. In Haemophilia B, factor IX is deficient. Factor VIII participates in blood coagulation; it is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids forms a complex that converts factor X to the activated form Xa. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. Prothrombin producing platelets in such persons are not found in very low concentration.