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Sickle cell anaemia is: (1) characterized by elongated sickle like RBCs with a nucleus

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Sickle cell anaemia is:

(1) characterized by elongated sickle like RBCs with a nucleus

(2) caused by substitution of valine by glutamic acid in the beta globin chain of haemoglobin

(3) an autosomal linked dominant trait

(4) caused by a change in a single base pair of DNA

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Correct answer: (4) caused by a change in a single base pair of DNA

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