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In Down's syndrome, Karyotyping has shown that the disorder is associated with trisomy of chromosome number-21 usually due to

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In Down's syndrome, Karyotyping has shown that the disorder is associated with trisomy of chromosome number-21 usually due to

(1) non-disjunction during formation of egg cells and sperm cells

(2) non-disjunction during egg-cell formation

(3) addition of extra chromosome during mitosis of the zygote

(4) non-disjunction during sperm-cell formation

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Correct answer: (1) non-disjunction during formation of egg cells and sperm cells

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